OPN gene polymorphism (Ala250) and lower serum OPN levels are associated with urolithiasis
نویسندگان
چکیده
منابع مشابه
OPN gene polymorphism and the serum OPN levels confer the susceptibility and prognosis of ischemic stroke in Chinese patients.
AIM To investigate the association of Osteopontin (OPN) gene polymorphism and serum thrombin-cleaved OPN level with the susceptibility to ischemic stroke (IS) and its prognosis. METHODS A total of 377 patients with IS and 551 healthy individuals were recruited. The OPN gene polymorphisms at -156 G>GG, -443 C>T and -66 T>G were genotyped. Serum full-length and the thrombin-cleaved OPN were det...
متن کاملExpression of OPN in human cancer 3. Expression of OPN splice variants in human cancers 4. Polymorphism of OPN and OPN splice variants in cancers
Human osteopontin (OPN) is a glycosylated phosphoprotein which is expressed in a variety of tissues in the body. In recent years, accumulating evidence has indicated that the aberrant expression of OPN is closely associated with tumourigensis, progression and most prominently with metastasis in several tumour types. In this review, we present the current knowledge on the expression profiles of ...
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Metabolic syndrome (MetS) is characterized by a cluster of cardiovascular risk factors that include: abdominal obesity, dyslipidaemia, hypertension, insulin resistance and impaired glucose tolerance. Recent genome wide association studies have identified several susceptibility regions involved in lipid metabolism that are also associated with MetS. We have explored the association of 9 genetic ...
متن کاملRoles of Osteopontin Gene Polymorphism (rs1126616), Osteopontin Levels in Urine and Serum, and the Risk of Urolithiasis: A Meta-Analysis
Objective. Previous studies have investigated the relationships between osteopontin gene polymorphism rs1126616 and OPN levels and urolithiasis, but the results were controversial. Our study aimed to clarify such relationships. Methods. A meta-analysis was performed by searching the databases Pubmed, Embase, and Web of Science for relevant studies. Crude odds ratios (ORs) or standardised mean d...
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This whitepaper presents a summary of the clinical studies investigating the end-user benefits of the new signal processing introduced in Oticon Opn on cognitive effort, memory recall, and speech recognition performance. Among the new signal processing, a new noise reduction algorithm named OpenSound Navigator (OSN), is introduced. It belongs to a new technology class of its own, the Multiple S...
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ژورنال
عنوان ژورنال: Renal Failure
سال: 2013
ISSN: 0886-022X,1525-6049
DOI: 10.3109/0886022x.2013.794431